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WATCH: ESPN's 'Big Game Breakdown' of Oregon vs. Duke

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Elgin Cook could be the X-factor for the Ducks.

ESPN's Seth Greenberg takes a look at the huge Oregon Ducks - Duke Blue Devils matchup in the Sweet 16.

While it's been a crazy NCAA Tournament already, Oregon vs. Duke could prove to be one of the best games yet -- and a huge opportunity on the national stage for the Ducks.

Greenberg breaks down the Ducks' horn set, which stretches and pressures a defense. On the other side, he says Duke will need big games not only from Grayson Allen and Brandon Ingram, but Luke Kennard and Marshall Plumlee.

For Oregon, the key to the game is to get to the offensive glass, while for Duke it's pushing the ball down the floor, spreading the court and shooting the three.

Greenberg says Elgin Cook is the X-factor for the Ducks.

The game is being played at the Honda Center in Anaheim, California. Tipoff is set for Thursday, 6:55 P.M. Pacific on TBS.